Web27 iun. 2024 · Proximal GATA-binding sites are essential for human HSD3B1 gene transcription in the placenta The enzyme 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD) is involved in the synthesis of active steroid hormones. Two human 3β-HSD isoforms are expressed in a tissue-specific pattern. Web22 nov. 2024 · They are composed of a DNA-binding domain that recognizes specific DNA sequence motifs, an optional signal-sensing domain that can alter TF activity after integrating signals from ligand binding, catalytic activity, protein interaction or post-translational modification, and a trans-activating domain that translates all these cellular …
Sensitivity of transcription factors to DNA methylation - PMC
WebJASPARis an open-access database of curated, non-redundant transcription factor (TF) binding profiles stored as position frequency matrices (PFMs) and TF flexible models … WebAbstract. Members of the GATA family of transcription factors, which are related by a high degree of amino acid sequence identity within their zinc finger DNA-binding domains, … csudh disability staff
JASPAR 2024 motif discovery pipeline and motif annotation
WebOther C4 zinc finger-type factors. C4-GATA-related. MA0037.4. Gata3. Mus musculus. Other C4 zinc finger-type factors. C4-GATA-related. Showing 4 profiles of page 1 from 1 pages. Web(G) JASPAR binding motif of GATA3. (H) Relative Gata3 mRNA expression in BMDMs from WT, Ucp2 −/− , or Irg1 −/− mice treated with vehicle or IL-33 (10 ng/mL for 5 days) … Web18 aug. 2024 · Abstract. During cellular reprogramming, the pioneer transcription factor GATA3 binds chromatin, and in a context-dependent manner directs local chromatin remodeling and enhancer formation. Here, we use high-resolution nucleosome mapping in human cells to explore the impact of the position of GATA motifs on the surface of … early sessions 1978 let me be your baby