WebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. CYP17A1 INFORMATION. Proteini. Full gene name according to HGNC. Cytochrome P450 family … WebCyp17a1: Gene Name: Cytochrome P450, family 17, subfamily a, polypeptide 1: Aliases: Cyp17, p450c17: RefSeq: NC_000085.6 NT_039687.8: Ensembl: …
CYP19A1 癌基因 - 癌症123
WebCYP11A1 (D8F4F) Rabbit mAb. #14217. 使用 CYP11A1 (D8F4F) Rabbit mAb（绿色）对 NCI-H295R（左，阳性）和 SW-13（右，阴性）细胞进行共聚焦免疫荧光分析。. 肌动蛋 … WebCYP17A1 is strongly expressed in half about of human prostate carcinomas, implying an intracellular androgen synthesis by cancer cells. Abiraterone effectively blocked nuclear … chinees nasi
Cyp17a1 - PCR Primer Pair - SYBR PrimePCR Bio-Rad
WebThe CYP17A1 gene provides instructions for making a member of the cytochrome P450 enzyme family. Like other cytochrome P450 enzymes, CYP17A1 is involved in the … WebJul 30, 2024 · Background 17α-Hydroxylase deficiency is a recessively inherited autosomal disease caused by mutations in the CYP17A1 gene. It is a rare disease and accounts for approximately 1% of congenital adrenal cortex hyperplasias. Inhibition of 17α-hydroxylase causes low levels of cortisol and high levels of adrenocorticotropic hormone in the blood … CYP17A1 is a member of the cytochrome P450 superfamily of enzymes localized in the endoplasmic reticulum. Proteins in this family are monooxygenases that catalyze synthesis of cholesterol, steroids and other lipids and are involved in drug metabolism. CYP17A1 has both 17α-hydroxylase activity (EC … See more Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the … See more Gene The CYP17A1 gene resides on chromosome 10 at the band 10q24.3 and contains 8 exons. The cDNA of this gene spans a length of … See more Mutations in this gene are associated with rare forms of congenital adrenal hyperplasia, specifically 17α-hydroxylase deficiency/17,20-lyase deficiency See more • Pregnenolone • 17α-Hydroxypregnenolone • Progesterone • 17α-Hydroxyprogesterone See more Expression of CYP17A1 has been found in all of the traditional steroidogenic tissues except the placenta, including the zona reticularis See more CYP17A1 inhibitors Currently, the FDA has approved only one CYP17A1 inhibitor, abiraterone, which contains a steroidal scaffold that is similar to the endogenous … See more • Biology portal • Steroidogenic enzyme • Cytochrome P450 oxidoreductase deficiency See more grand canyon title az